Accuracy and cutoff values of delayed heart to mediastinum ratio with 123I-metaiodobenzylguanidine cardiac scintigraphy for Lewy body disease diagnoses

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Accuracy and cutoff values of delayed heart to mediastinum ratio with 123I-metaiodobenzylguanidine cardiac scintigraphy for Lewy body disease diagnoses

BACKGROUND Different studies have found diminished cardiac metaiodobenzylguanidine (MIBG) uptake in Lewy body (LB) related conditions (Parkinson's disease (PD) and Lewy body dementia (LBD)). However, delayed heart/mediastinum (d-H/M) ratio diagnostic cutoff points are debated in parkinsonian syndromes. METHODS We performed a monocentric retrospective analysis on 62 consecutive parkinsonian pa...

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metaiodobenzylguanidine cardiac scintigraphy for Lewy body disease diagnoses

Background: Different studies have found diminished cardiac metaiodobenzylguanidine (MIBG) uptake in Lewy body (LB) related conditions (Parkinson’s disease (PD) and Lewy body dementia (LBD)). However, delayed heart/ mediastinum (d-H/M) ratio diagnostic cutoff points are debated in parkinsonian syndromes. Methods: We performed a monocentric retrospective analysis on 62 consecutive parkinsonian p...

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Uptake index of 123I-metaiodobenzylguanidine myocardial scintigraphy for diagnosing Lewy body disease

Objective(s): Iodine-123 metaiodobenzylguanidine (123I-MIBG) myocardial scintigraphy has been used to evaluate cardiac sympathetic denervation in Lewy body disease (LBD), including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). The heart-tomediastinum ratio (H/M) in PD and DLB is significantly lower than that in Parkinson’s plus syndromes and Alzheimer’s disease. Although this ra...

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uptake index of 123i-metaiodobenzylguanidine myocardial scintigraphy for diagnosing lewy body disease

objective(s): iodine-123 metaiodobenzylguanidine (123i-mibg) myocardial scintigraphy has been used to evaluate cardiac sympathetic denervation in lewy body disease (lbd), including parkinson’s disease (pd) and dementia with lewy bodies (dlb). the heart-tomediastinum ratio (h/m) in pd and dlb is significantly lower than that in parkinson’s plus syndromes and alzheimer’s disease. although this ra...

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Uptake Index of 123I-metaiodobenzylguanidine Myocardial Scintigraphy for Diagnosing Lewy Body Disease

OBJECTIVES Iodine-123 metaiodobenzylguanidine (123I-MIBG) myocardial scintigraphy has been used to evaluate cardiac sympathetic denervation in Lewy body disease (LBD), including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The heart-to-mediastinum ratio (H/M) in PD and DLB is significantly lower than that in Parkinson's plus syndromes and Alzheimer's disease. Although this rati...

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ژورنال

عنوان ژورنال: BMC Neurology

سال: 2015

ISSN: 1471-2377

DOI: 10.1186/s12883-015-0338-9